The best thing to do is to look at reviews of the vehicle you are considering. The Pilot is considerably larger than the Accord and with that comes higher fuel costs and tighter fitting parking!
(Pilot fuel economy: 17 city/22 highway; Accord: 24 city/34 highway)
However, you will also get more room inside and more comfort for the grandkids in a Pilot.
Here are some reviews to check out:
After you read the reviews and do some research online, make sure you head to a dealer to take a test drive before you buy anything. Actually spending seat time in a car is more important than all the reading out there.
Make sure you know about how it will affect the current loan you have (if you have one). Since your Accord is so new, it might mean that you end up losing money doing a trade in at this time.